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1.
J Am Acad Dermatol ; 83(1): 1-14, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32229279

RESUMO

Leprosy, also known as Hansen's disease, is a curable infectious disease that remains endemic in >140 countries around the world. Despite being declared "eliminated" as a global public health problem by the World Health Organization in the year 2000, approximately 200,000 new cases were reported worldwide in 2017. Widespread migration may bring leprosy to nonendemic areas, such as North America. In addition, there are areas in the United States where autochthonous (person-to-person) transmission of leprosy is being reported among Americans without a history of foreign exposure. In the first article in this continuing medical education series, we review leprosy epidemiology, transmission, classification, clinical features, and diagnostic challenges.


Assuntos
Hanseníase/diagnóstico , Diagnóstico Diferencial , Doenças Endêmicas , Saúde Global , Humanos , Incidência , Hanseníase/classificação , Hanseníase/epidemiologia , Hanseníase/microbiologia , Prevalência
2.
J Am Acad Dermatol ; 83(1): 17-30, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32244016

RESUMO

In the second article in this continuing medical education series, we review the treatment of leprosy, its immunologic reactions, and important concepts, including disease relapse and drug resistance. A fundamental understanding of the treatment options and management of neuropathic sequelae are essential to reduce disease burden and improve patients' quality of life.


Assuntos
Hanseníase/complicações , Hanseníase/tratamento farmacológico , Antibacterianos/uso terapêutico , Efeitos Psicossociais da Doença , Farmacorresistência Bacteriana , Quimioterapia Combinada , Feminino , Humanos , Hanseníase/imunologia , Hanseníase/patologia , Gravidez , Complicações Infecciosas na Gravidez/tratamento farmacológico , Qualidade de Vida , Recidiva
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